Multidisciplinary team focused on understanding substance use disorders
Research in the Drug Lab focuses on mechanism-based determinants and modification of addictive behaviors. Our lab uses rigorous human experimental approaches, medications and pharmacological probes, multi-modal magnetic resonance imaging, neuromodulation, and behavioral, subjective and physiological endpoints to investigate hypothesized relationships.
There are several ongoing projects in the lab. Students at various levels of training (e.g. postdoctoral, graduate, medical, undergraduate) are routinely involved in our research and obtain mentored scientific experiences. Beyond these studies, we are actively engaged in several other collaborative projects with other labs at Wayne State University and across the country.
Stress can increase and/or maintain substance seeking and use in laboratory animals, but until now there have been no well-controlled human studies. We seek to understand how stress impact use of opioids in current opioid users.